Decades of research continues to demonstrate the benefits of exercise as a nondrug component of fibromyalgia management. Fibromyalgia is a chronic condition affecting more than five million American adults, mostly female. Symptoms include widespread musculoskeletal pain, profound fatigue, sleep disturbances, as well as potential cognitive impairments and depression. Research studies have investigated how people with fibromyalgia respond to traditional aerobic conditioning, strength training, and more mindful modalities such as Yoga, Pilates and tai chi.